As a second-generation click reaction, SuFEx offers high selectivity, efficiency, and biocompatibility, empowering biomedicine, chemical biology, and materials science. It enables vivo macromolecular coupling and has driven clinical-stage candidates for cancer and tuberculosis.
Shortening the cycle from concept to validation, building compound libraries, and advancing drug and material R&D.
High reliability and selectivity ensure reproducibility, efficiency, and outcome certainty.
Efficient, precise, and physiologically stable aqueous bioconjugation for ADCs and probe design.
Constructing high-performance, degradable polysulfates and polysulfonates for green chemistry and sustainability.
Centered on S(VI)–F reactive groups, we offer diverse SuFEx building blocks—including sulfonyl fluorides, fluorosulfonates, N-containing S–F reagents, and polyfunctional constructs—powering drug discovery, bioconjugation, probe design, and functional materials.
Consult on SuFEx custom synthesis services
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