SuFEx Full-Process Services

Sulfur(VI) Fluoride Exchange (SuFEx) Chemistry Platform for Biomedicine, Chemical Biology, and Advanced Materials R&D.

SuFEx Services Overview

As a second-generation click reaction, SuFEx offers high selectivity, efficiency, and biocompatibility, empowering biomedicine, chemical biology, and materials science. It enables vivo macromolecular coupling and has driven clinical-stage candidates for cancer and tuberculosis.

SuFEx Service Capabilities

Building Block Selection / Molecular Design
Match SVI-F building blocks, covalent warheads, or reaction pathways according to project goals.
01
Synthesis & QC
Provide target molecule synthesis, purity testing, structural confirmation, and quality reports.
02
Scaling Support
Support scale-up preparation and batch stability for industrialization or follow-up research.
03

Technical Advantages

Accelerating Innovation and Discovery

Shortening the cycle from concept to validation, building compound libraries, and advancing drug and material R&D.

Enhancing Synthesis Success and Predictability

High reliability and selectivity ensure reproducibility, efficiency, and outcome certainty.

Expanding Chemical Space

Efficient, precise, and physiologically stable aqueous bioconjugation for ADCs and probe design.

Advanced Polymer Materials

Constructing high-performance, degradable polysulfates and polysulfonates for green chemistry and sustainability.

SuFEx Building Block Products

Centered on S(VI)–F reactive groups, we offer diverse SuFEx building blocks—including sulfonyl fluorides, fluorosulfonates, N-containing S–F reagents, and polyfunctional constructs—powering drug discovery, bioconjugation, probe design, and functional materials.


Workflow

01
Consultation & Needs Assessment
Confirmation of project objectives and modular strategies; Confirmation of project parameters.
02
Design / Quote / Implementation Plan
Confirmation of project objectives and modular strategies; Confirmation of project parameters.
03
Synthesis & Quality Control (QC)
Confirmation of project objectives and modular strategies; Confirmation of project parameters.
04
Delivery & Reporting
Confirmation of project objectives and modular strategies; Confirmation of project parameters.
05
After-sales Support
Confirming project objectives, modular strategies, and parameters.

Consult on SuFEx custom synthesis services

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